لسلام عليكم ورحمة الله وبركاته
تحية وتقدير لحضرتك dr_ahmed
فكرة حضرتك رائعة وانا متحمسة ليها جدا
لانى بحب microbiology جدا
وياريت تسمحلى بسؤال
اولا شكرا جزيلا يا دكتورة
تحية وتقدير لحضرتك dr_ahmed
فكرة حضرتك رائعة وانا متحمسة ليها جدا
لانى بحب microbiology جدا
وياريت تسمحلى بسؤال
خاص ب streptcocci
as it clear to be understood
the hyaluronic acid capsule is one of it's virulence factors
as it act as immunological mask to avoid the phagositosis
and on of the invasive factors of strept is
hyaluronidase enz
my question is
:is that enz affect it's one capsule
and if that occure
is it logic that one of it's virulence factors cancelled another imp one
as it clear to be understood
the hyaluronic acid capsule is one of it's virulence factors
as it act as immunological mask to avoid the phagositosis
and on of the invasive factors of strept is
hyaluronidase enz
my question is
:is that enz affect it's one capsule
and if that occure
is it logic that one of it's virulence factors cancelled another imp one
اولا شكرا جزيلا يا دكتورة
ثانيا سؤالك سؤال جميل جدا
وخلينا نجاوبة ببساطة من غير دخول في تفاصيل ماتهمكيش كطالب في سنه تالته
الفكرة ببساطة
ان مش كل ال strains of strept عندها كبسول
بعضها بس
و برده نفس الكلام بالنسبة للانزيم بالظبط مش كل الانواع بتفرزه
ولما بنقول ال virulence factors
فاحنا هنا بنتكلم عن كل العوامل اللي موجوده في كل ال strains
ومش شرط تكون في كل نوع
وصلت؟؟
ولو حبيتي تقري زياده "ده لو فاضية لا سمح الله"
شوفي ال لينك دي:
http://en.wikipedia.org/wiki/Streptococcus_pyogenes
هاتلاقي فيها الكلام ده:
It is widely assumed that hyaluronidase facilitates the spread of the bacteria through tissues by breaking down hyaluronic acid, an important component of connective tissue. However, very few isolates of S. pyogenes are capable of secreting active hyaluronidase due to mutations in the gene that encode the enzyme. Moreover, the few isolates that are capable of secreting hyaluronidase do not appear to need it to spread through tissues or to cause skin lesions.[8] Thus, the true role of hyaluronidase in pathogenesis, if any, remains unknown.
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